What is CBMcarb-DB ?
This database contains the three-dimensional structures of Carbohydrate Binding Modules (CBM) of proteins that have been crystallized with their ligands. The type of proteins, along with the bound Glycan are provided. Links are available to access the information about the original article (Medline), the protein sequence, related structural information (Swissprot, PDB) ....
This database contains the three-dimensional structures of Carbohydrate Binding Modules (CBM) of proteins that have been crystallized with their ligands. The type of proteins, along with the bound Glycan are provided. Links are available to access the information about the original article (Medline), the protein sequence, related structural information (Swissprot, PDB) ....
What are CBMs ?
CBMs can be defined as discrete auxiliary protein modules with a non-catalytic carbohydrate binding function. CBMs are typically associated to modular enzymes but can also be found isolated from a polypeptide chain or associated to other non-enzymatic proteins. Some lectins and LysM domains are also classified as CBMs. CBMs have been grouped into families based on amino acid sequence similarities. These modules show a highly diverse range of carbohydrate binding specificities and exert critical functions in enhancing enzyme catalytic efficiency (e.g. substrate targeting), as carbohydrate sensing domains or as adhesion molecules (e.g. mediating bacterial adhesion to host cell surface). CBMs are also used in different biotechnological applications.
CBMs can be defined as discrete auxiliary protein modules with a non-catalytic carbohydrate binding function. CBMs are typically associated to modular enzymes but can also be found isolated from a polypeptide chain or associated to other non-enzymatic proteins. Some lectins and LysM domains are also classified as CBMs. CBMs have been grouped into families based on amino acid sequence similarities. These modules show a highly diverse range of carbohydrate binding specificities and exert critical functions in enhancing enzyme catalytic efficiency (e.g. substrate targeting), as carbohydrate sensing domains or as adhesion molecules (e.g. mediating bacterial adhesion to host cell surface). CBMs are also used in different biotechnological applications.